Infection of zebrafish larvae with human norovirus and evaluation of the in vivo efficacy of small-molecule inhibitors

Jana Van Dycke, Arno Cuvry, Jan Knickmann, Annelii Ny, Sebastian Rakers, Stefan Taube, Peter de Witte, Johan Neyts, Joana Rocha-Pereira

Published: 2021-04-08 DOI: 10.1038/s41596-021-00499-0

zebrafish larvae

human norovirus

viral replication

small-molecule inhibitors

antiviral efficacy

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Supplementary information

Reporting Summary

Supplementary Video 1

Clipping of the microinjection needle

Supplementary Video 2

Correct size bolus

Supplementary Video 3

Microinjection in the yolk of 3 dpf zebrafish larvae

Supplementary Video 4

Dechorionation of 2 dpf zebrafish larvae

Supplementary Video 5

Microinjection in the pericardial cavity of 3 dpf zebrafish larvae

Efficient and safe single-cell cloning of human pluripotent stem cells using the CEPT cocktail

Profiling native pulmonary basement membrane stiffness using atomic force microscopy

Genetic circuit design automation with Cello 2.0

Synthesis of siRNA nanoparticles to silence plaque-destabilizing gene in atherosclerotic lesional macrophages

Scalable dual-omics profiling with single-nucleus chromatin accessibility and mRNA expression sequencing 2 (SNARE-seq2)

A practical guide to scanning light-field microscopy with digital adaptive optics

Effective high-throughput isolation of fully human antibodies targeting infectious pathogens

Improved sampling and DNA extraction procedures for microbiome analysis in food-processing environments

MOF-derived nanoporous carbons with diverse tunable nanoarchitectures

Tutorial: a statistical genetics guide to identifying HLA alleles driving complex disease

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Supplementary information

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