An analytical workflow for dynamic characterization and quantification of metal-bearing nanomaterials in biological matrices

Iseult Lynch, Peng Zhang, Fazel Abdolahpur Monikh, Zhiling Guo, Martina G. Vijver, Eugenia Valsami-Jones, Willie J. G. M. Peijnenburg

Published: 2022-06-28 DOI: 10.1038/s41596-022-00701-x

Quantification

Metal-bearing nanomaterials

Biological matrices

Dynamic characterization

Analytical workflow

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References

Fadeel, B. et al. Advanced tools for the safety assessment of nanomaterials. Nat. Nanotechnol. 13, 537–543 (2018).
Drobne, D., Novak, S., Talaber, I., Lynch, I. & Kokalj, A. The biological fate of silver nanoparticles from a methodological perspective. Materials 11, 957 (2018).
Abdolahpur Monikh, F. et al. Particle number-based trophic transfer of gold nanomaterials in an aquatic food chain. Nat. Commun. 12, 899 (2021).
Chetwynd, A. J., Zhang, W., Thorn, J. A., Lynch, I. & Ramautar, R. The nanomaterial metabolite corona determined using a quantitative metabolomics approach: a pilot study. Small 16, 2000295 (2020).
Abdolahpur Monikh, F. et al. Method for extraction and quantification of metal-based nanoparticles in biological media: number-based biodistribution and bioconcentration. Environ. Sci. Technol. 53, 946–953.
Abdolahpur Monikh, F. et al. The stochastic association of nanoparticles with algae at the cellular level: effects of NOM, particle size and particle shape. Ecotoxicol. Environ. Saf. 218, 112280 (2021).
Arenas-Lago, D., Abdolahpur Monikh, F., Vijver, M. G. & Peijnenburg, W. J. G. M. Dissolution and aggregation kinetics of zero valent copper nanoparticles in (simulated) natural surface waters: simultaneous effects of pH, NOM and ionic strength. Chemosphere 226, 841–850 (2019).
Werlin, R. et al. Biomagnification of cadmium selenide quantum dots in a simple experimental microbial food chain. Nat. Nanotechnol. 6, 65–71 (2011).
Abdolahpur Monikh, F. et al. Development of methods for extraction and analytical characterization of carbon-based nanomaterials (nanoplastics and carbon nanotubes) in biological and environmental matrices by asymmetrical flow field-flow fractionation. Environ. Pollut. 255, 113304 (2019).
Abdolahpur Monikh, F., Chupani, L., Vijver, M. G., Vancová, M. & Peijnenburg, W. J. G. M. Analytical approaches for characterizing and quantifying engineered nanoparticles in biological matrices from an (eco)toxicological perspective: old challenges, new methods and techniques. Sci. Total Environ. 660, 1283–1293 (2019).
Milosevic, A., Romeo, D. & Wick, P. Understanding nanomaterial biotransformation: an unmet challenge to achieving predictive nanotoxicology. Small 16, 1907650 (2020).
Abdolahpur Monikh, F. et al. Engineered nanoselenium supplemented fish diet: toxicity comparison with ionic selenium and stability against particle dissolution, aggregation and release. Environ. Sci. Nano 7, 2325–2336 (2020).
Guo, Z. et al. Biotransformation modulates the penetration of metallic nanomaterials across an artificial blood–brain barrier model. Proc. Natl Acad. Sci. USA 118, 1–10 (2021).
Ma, Y. et al. Origin of the different phytotoxicity and biotransformation of cerium and lanthanum oxide nanoparticles in cucumber. Nanotoxicology 9, 262–270 (2015).
Rees, P., Wills, J. W., Brown, M. R., Barnes, C. M. & Summers, H. D. The origin of heterogeneous nanoparticle uptake by cells. Nat. Commun. 10, 2341 (2019).
Santra, S. et al. TAT conjugated, FITC doped silica nanoparticles for bioimaging applications. Chem. Commun. 2810 (2004). http://doi.org/10.1039/b411916a
Salvati, A. et al. Experimental and theoretical comparison of intracellular import of polymeric nanoparticles and small molecules: toward models of uptake kinetics. Nanomed. Nanotechnol. Biol. Med. 7, 818–826 (2011).
Zhang, P., Misra, S., Guo, Z., Rehkämper, M. & Valsami-Jones, E. Stable isotope labeling of metal/metal oxide nanomaterials for environmental and biological tracing. Nat. Protoc. 14, 2878–2899 (2019).
Clark, N. J., Clough, R., Boyle, D. & Handy, R. D. Development of a suitable detection method for silver nanoparticles in fish tissue using single particle ICP-MS. Environ. Sci. Nano 6, 3388–3400 (2019).
Sung, H. K. et al. Analysis of gold and silver nanoparticles internalized by zebrafish (Danio rerio) using single particle-inductively coupled plasma-mass spectrometry. Chemosphere 209, 815–822 (2018).
Jiménez-Lamana, J., Wojcieszek, J., Jakubiak, M., Asztemborska, M. & Szpunar, J. Single particle ICP-MS characterization of platinum nanoparticles uptake and bioaccumulation by: Lepidium sativum and Sinapis alba plants. J. Anal. Spectrom. 31, 2321–2329 (2016).
Xu, X., Chen, J., Li, B., Tang, L. & Jiang, J. Single particle ICP-MS-based absolute and relative quantification of E. coli O157 16S rRNA using sandwich hybridization capture. Analyst 144, 1725–1730 (2019).
Loeschner, K. et al. Detection and characterization of silver nanoparticles in chicken meat by asymmetric flow field flow fractionation with detection by conventional or single particle ICP-MS. Anal. Bioanal. Chem. 405, 8185–8195 (2013).
Corte Rodríguez, M., Álvarez-Fernández García, R., Blanco, E., Bettmer, J. & Montes-Bayón, M. Quantitative evaluation of cisplatin uptake in sensitive and resistant individual cells by single-cell ICP-MS (SC-ICP-MS). Anal. Chem. 89, 11491–11497 (2017).
Abdolahpur Monikh, F. et al. A dose metrics perspective on the association of gold nanomaterials with algal cells. Environ. Sci. Technol. Lett. 6, 732–738 (2019).
Li, S., Liu, Y. & Ma, Q. Nanoparticle-based electrochemiluminescence cytosensors for single cell level detection. TrAC Trends Anal. Chem. 110, 277–292 (2019).
Lee, S. et al. Nanoparticle size detection limits by single particle ICP-MS for 40 elements. Environ. Sci. Technol. 48, 10291–10300 (2014).
Talbot, M. J. & White, R. G. Methanol fixation of plant tissue for scanning electron microscopy improves preservation of tissue morphology and dimensions. Plant Methods 9, 36 (2013).
Filipe, V., Hawe, A. & Jiskoot, W. Critical evaluation of nanoparticle tracking analysis (NTA) by NanoSight for the measurement of nanoparticles and protein aggregates. Pharm. Res. http://doi.org/10.1007/s11095-010-0073-2 (2010).
Montaño, M. D., Olesik, J. W., Barber, A. G., Challis, K. & Ranville, J. F. Single particle ICP-MS: advances toward routine analysis of nanomaterials. Anal. Bioanal. Chem. 408, 5053–5074 (2016).
Johnson, M. E. et al. Combining secondary ion mass spectrometry image depth profiling and single particle inductively coupled plasma mass spectrometry to investigate the uptake and biodistribution of gold nanoparticles in Caenorhabditis elegans. Anal. Chim. Acta 1175, 338671 (2021).
Wagener, S. et al. Determination of nanoparticle uptake, distribution, and characterization in plant root tissue after realistic long-term exposure to sewage sludge using information from mass spectrometry. Environ. Sci. Technol. 53, 5416–5426 (2019).
Singh, C. et al. Zinc oxide NM-110, NM-111, NM-112, NM-113 characterisation and test item preparation, NM-series of representative manufactured nanomaterials. EUR - Scientific and Technical Research Reports (2011).
Rasmussen, K. et al. Titanium Dioxide, NM-100, NM-101, NM-102, NM-103, NM-104, NM-105: Characterisation and Physico- Chemical Properties. JRC (2014).
Naito, H. et al. Isolation of tissue-resident vascular endothelial stem cells from mouse liver. Nat. Protoc. 15, 1066–1081 (2020).
Takahashi, T. Routine management of microalgae using autofluorescence from chlorophyll. Molecules 24, 4441 (2019).
Johnson, M. E. et al. Separation, sizing, and quantitation of engineered nanoparticles in an organism model using inductively coupled plasma mass spectrometry and image analysis. ACS Nano 11, 526–540 (2017).
Peters, R. J. B. et al. Development and validation of single particle ICP-MS for sizing and quantitative determination of nano-silver in chicken meat. Anal. Bioanal. Chem. 406, 3875–3885 (2014).
Dan, Y. et al. Characterization of gold nanoparticle uptake by tomato plants using enzymatic extraction followed by single-particle inductively coupled plasma–mass spectrometry analysis. Environ. Sci. Technol. 49, 3007–3014 (2015).
Velimirovic, M. et al. Accurate quantification of TiO2 nanoparticles in commercial sunscreens using standard materials and orthogonal particle sizing methods for verification. Talanta 215, 120921 (2020).
Hendriks, L., Gundlach-Graham, A. & Günther, D. Analysis of inorganic nanoparticles by single-particle inductively coupled plasma time-of-flight mass spectrometry. CHIMIA Int. J. Chem. 72, 221–226 (2018).
Praetorius, A. et al. Single-particle multi-element fingerprinting (spMEF) using inductively-coupled plasma time-of-flight mass spectrometry (ICP-TOFMS) to identify engineered nanoparticles against the elevated natural background in soils. Environ. Sci. Nano 4, 307–314 (2017).
Zhang, P. et al. Biotransformation of ceria nanoparticles in cucumber plants. ACS Nano 6, 9943–9950 (2012).
Zhang, P. et al. Comparative toxicity of nanoparticulate/bulk Yb2O3 and YbCl3 to cucumber (Cucumis sativus). Environ. Sci. Technol. 46, 1834–1841 (2012).
Schavkan, A. et al. Number concentration of gold nanoparticles in suspension: SAXS and spICPMS as traceable methods compared to laboratory methods. Nanomaterials 9, 502 (2019).
Petersen, E. J. et al. Determining what really counts: modeling and measuring nanoparticle number concentrations. Environ. Sci. Nano 6, 2876–2896 (2019).

An analytical workflow for dynamic characterization and quantification of metal-bearing nanomaterials in biological matrices

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