A surgical mouse model of neonatal pressure overload by transverse aortic constriction

Mona Malek Mohammadi, Aya Abouissa, Joerg Heineke

Published: 2020-12-15 DOI: 10.1038/s41596-020-00434-9

neonatal mouse model

pressure overload

transverse aortic constriction

cardiac regeneration

therapeutic strategies

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Supplementary information

Supplementary Information

Supplementary Materials and Methods.

Reporting Summary

Supplementary Video 1

Video demonstrating the nTAC procedure

Generation of mouse–human chimeric embryos

Genome-wide quantification of transcription factor binding at single-DNA-molecule resolution using methyl-transferase footprinting

Generation of CRISPR–Cas9-mediated genetic knockout human intestinal tissue–derived enteroid lines by lentivirus transduction and single-cell cloning

A puromycin-dependent activity-based sensing probe for histochemical staining of hydrogen peroxide in cells and animal tissues

Decoding personal biotic and abiotic airborne exposome

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Bioengineering human intestinal mucosal grafts using patient-derived organoids, fibroblasts and scaffolds

Biomimetic tail-to-head terpene cyclizations using the resorcin[4]arene capsule catalyst

Neuroscience robotics for controlled induction and real-time assessment of hallucinations

Scanorama: integrating large and diverse single-cell transcriptomic datasets

Single-cell RNA sequencing (scRNA-seq)（单细胞RNA测序）

Data integration（数据集成）

Heterogeneity（异质性）

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References

Supplementary information

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A surgical mouse model of neonatal pressure overload by transverse aortic constriction

Supplementary information

Supplementary Information

Reporting Summary

Supplementary Video 1

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